Total Synthesis of Ochnaflavone

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dc.contributor.authorNdoile, Monica
dc.contributor.authorvan Heerden, Fanie
dc.date.accessioned2018-09-10T11:36:16Z
dc.date.available2018-09-10T11:36:16Z
dc.date.issued2013
dc.description.abstractThe first total syntheses of ochnaflavone, an asymmetric biflavone consisting of apigenin and luteolin moieties, and the permethyl ether of 2,3,2'',3''-tetrahydroochnaflavone have been achieved. The key steps in the synthesis of ochnaflavone were the formation of a diaryl ether and ring cyclization of an ether-linked dimeric chalcone to assemble the two flavone nuclei. Optimal experimental conditions for the oxidative cyclization to form ochnaflavone were established.en_US
dc.identifier.urihttp://hdl.handle.net/20.500.11810/4869
dc.subjectbiflavoneen_US
dc.subjectdiaryl etheren_US
dc.subjectnatural productsen_US
dc.subjectnucleophilic aromatic substitutionen_US
dc.subjectochnaflavoneen_US
dc.subjecttetrahydroochnaflavoneen_US
dc.titleTotal Synthesis of Ochnaflavoneen_US
dc.typeJournal Article, Peer Revieweden_US
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