Flavonoids from Erythrina Schliebenii

Simple item page
dc.contributor.authorNyandoro, Stephen S.
dc.contributor.authorMunissi, Joan J.E
dc.contributor.authorKombo, Msim
dc.contributor.authorMgina, Clarence A
dc.contributor.authorPan, FangFang
dc.contributor.authorGruhonjic, Amra
dc.contributor.authorFitzpatrick, Paul A.
dc.contributor.authorLu, Yu
dc.contributor.authorWang, Bin
dc.contributor.authorRissanen, Kari
dc.contributor.authorErdelyi, Mate
dc.date.accessioned2018-11-08T10:12:06Z
dc.date.available2018-11-08T10:12:06Z
dc.date.issued2017-01-23
dc.description.abstractPrenylated and O-methylflavonoids including one new pterocarpan (1), three new isoflavones (2–4), and nineteen known natural products (5–23) were isolated and identified from the root, stem bark, and leaf extracts of Erythrina schliebenii. The crude extracts and their constituents were evaluated for antitubercular activity against Mycobacterium tuberculosis (H37Rv strain), showing MICs of 32–64 μg mL–1 and 36.9–101.8 μM, respectively. Evaluation of their toxicity against the aggressive human breast cancer cell line MDA-MB-231 indicated EC50 values of 13.0–290.6 μM (pure compounds) and 38.3 to >100 μg mL–1 (crude extracts).en_US
dc.description.sponsorshipSwedish Research Council (SRC)en_US
dc.identifier.citationFlavonoids from Erythrina schliebenii Stephen S. Nyandoro, Joan J. E. Munissi, Msim Kombo, Clarence A. Mgina, Fangfang Pan, Amra Gruhonjic, Paul Fitzpatrick, Yu Lu, Bin Wang, Kari Rissanen, and Máté Erdélyi Journal of Natural Products 2017 80 (2), 377-383 DOI: 10.1021/acs.jnatprod.6b00839en_US
dc.identifier.doi10.1021/acs.jnatprod.6b00839
dc.identifier.urihttp://hdl.handle.net/20.500.11810/4970
dc.language.isoenen_US
dc.publisherAmerican Chemical Societyen_US
dc.subjectFlavonoids, Erythrina schliebeniien_US
dc.titleFlavonoids from Erythrina Schliebeniien_US
dc.typeJournal Article, Peer Revieweden_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
abstract Flavonoids from Erythrina Schliebenii.pdf
Size:
16.31 KB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Chemistry Department