Antibiotic Containing Poly Lactic Acid/Hydroxyapatite Biocomposite Coatings for Dental Implant Applications

dc.contributor.authorKaracan, Ipek
dc.contributor.authorMacha, Innocent J
dc.contributor.authorChoi, Gina
dc.contributor.authorCazalbou, Sophie
dc.contributor.authorBen-Nissan, Besim
dc.date.accessioned2019-02-15T19:25:28Z
dc.date.available2019-02-15T19:25:28Z
dc.date.issued2017-11
dc.description.abstractThe biodegradable and biocompatible antibiotic containing thin film composites are very appropriate biomaterials as coating materials for dental implants because of their adjustable drug loading and release rates for the prevention of implant related infections. Coralline hydroxyapatite (HAp) was loaded with gentamicin antibiotics and combined with a biodegradable polylactic acid (PLA) to form thin film composites. PLA-HAp, PLA-Gentamicin (GM) and PLA-HAp-GM composites were produced, and their dissolution studies were carried out in phosphate buffered saline under SINK conditions. It was observed that the coatings could be efficiently applied to titanium dental implants and the drug release rates can be efficiently controlled.en_US
dc.identifier.doidoi.org/10.4028/www.scientific.net/KEM.758.120
dc.identifier.issn1662-9795
dc.identifier.urihttp://hdl.handle.net/20.500.11810/5058
dc.language.isoenen_US
dc.publisherTrans Tech Publications Incen_US
dc.subjectCoating Dental Implants, Drug Release Studies, Hard Coral, Hydroxyapatite, PLA Thin Film Compositesen_US
dc.titleAntibiotic Containing Poly Lactic Acid/Hydroxyapatite Biocomposite Coatings for Dental Implant Applicationsen_US
dc.typeJournal Article, Peer Revieweden_US
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