Stephanostema Stenocarpum (Apocynaceae) Extract is a Potential Remedy for Bacterial Infections in Domestic Animals
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Date
2010-12
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Abstract
Stephanostema is a monotypic genus whose sole specie Stephanostema stenocarpum is endemic to
Tanzania. The liquid from boiled roots of this plant is being used by the local communities as a remedy of
stomach-ache related ailments. The aim of the study was to evaluate antimicrobial activity of S.
stenocarpum extracts against some common bacterial and fungal pathogens in domesticated animals and
examine whether the crude extracts found active have cytotoxic effect or not. The standard growth
inhibition technique was used for in vitro antimicrobial activity assay and the brine shrimp (BST) test was
used to evaluate cytotoxicity of the extracts. Ethanolic extracts exhibited bacterial inhibitory growth
activity against animal bacteria pathogens: Streptococcus agalactiae, Staphylococcus aureus, Salmonella
gallinarum and Escherichia coli, but not active against the fungal strains tested. The study also showed
that the extracts have no cytotoxicity effects. These results provide baseline information on the medicinal
potential of S. stenocarpum as a new potential source of veterinary medicines.
Description
Keywords
Stephanostema stenocarpum, Phytotherapy, Antibacterial, Antifungal, Cytotoxicity, Veterinary
Citation
Lyantagaye, S.L. and Magingo, F.S., 2012. Stephanostema stenocarpum (Apocynaceae) extract is a potential remedy for bacterial infections in domestic animals. Journal of Medicinal Plants Research, 6(35), pp.4915-4921.