Household Epidemics: Modelling Effects of Early Stage Vaccination

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dc.contributor.authorShaban, Nyimvua
dc.contributor.authorAndersson, Mikael
dc.contributor.authorSvensson, Åke
dc.contributor.authorBritton, Tom
dc.date.accessioned2016-09-21T17:24:23Z
dc.date.available2016-09-21T17:24:23Z
dc.date.issued2009
dc.description.abstractA Markovian susceptible - infectious - removed (SIR) epidemic model is considered in a community partitioned into households. A vaccination strategy, which is implemented during the early stages of the disease following the detection of infected individuals is proposed. In this strategy, the detection occurs while an individual is infectious and other susceptible household members are vaccinated without further delay. Expressions are derived for the influence on the reproduction numbers of this vaccination strategy for equal and unequal household sizes. We fit previously estimated parameters from influenza and use household distributions for Sweden and Tanzania census data. The results show that the reproduction number is much higher in Tanzania (6 compared with 2) due to larger households, and that infected individuals have to be detected (and household members vaccinated) after on average 5 days in Sweden and after 3.3 days in Tanzania, a much smaller difference.en_US
dc.identifier.citationShaban, N., Andersson, M., Svensson, Å. and Britton, T., 2009. Household epidemics: modelling effects of early stage vaccination. Biometrical Journal, 51(3), pp.408-419.en_US
dc.identifier.doi10.1002/bimj.200800172
dc.identifier.urihttp://hdl.handle.net/20.500.11810/4176
dc.language.isoenen_US
dc.publisherWileyen_US
dc.subjectDelay timeen_US
dc.subjectEpidemic modelen_US
dc.subjectHouseholden_US
dc.subjectReproduction numberen_US
dc.subjectVaccination strategyen_US
dc.titleHousehold Epidemics: Modelling Effects of Early Stage Vaccinationen_US
dc.typeJournal Article, Peer Revieweden_US
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