Efficacy of crude extract of Aloe secundiflora against Salmonella gallinarum in experimentally infected free-range chickens in Tanzania

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dc.contributor.authorWaihenya, R.K.
dc.contributor.authorMtambo, M.M.A.
dc.contributor.authorNkwengulila, Gamba
dc.contributor.authorMinga, U.M.
dc.date.accessioned2016-04-12T13:03:21Z
dc.date.available2016-04-12T13:03:21Z
dc.date.issued2002
dc.descriptionFull text can be accessed at http://www.sciencedirect.com/science/article/pii/S037887410100397Xen_US
dc.description.abstractThe ethnoveterinary use of Aloe species extract in free-range local chickens against fowl typhoid was investigated. Five-months-old local chickens, free of antibodies against fowl typhoid were used. The chickens were randomly assorted into five groups including pretreated and infected (G1, n=21), infected and untreated (G2, n=21), infected and treated (G3, n=21), untreated and uninfected (G4, n=10) and treated uninfected (G5, n=10). Groups 1, 2 and 3 were inoculated with 5.0×108 c.f.u/ml of Salmonella gallinarum, following which the chickens were monitored for 15 days. There was a delay on the occurrence of the clinical signs and reduced severity of the disease in the Aloe treated chickens (G1 and G3). The mortality rates were 23.8% (5/21) in G1 (pretreated and infected), 42.8% (9/21) in G2 (infected and untreated) and 14.2% (3/21) in G3 (infected and treated). Antibody levels were raised among the infected and untreated group (G2) while they remained relatively low in the Aloe treated groups (G1 and G3). However, there was a sharp increase in the levels of interleukin 6 (IL-6) in the Aloe treated groups (G1 and G3) as compared to the untreated group (G2) until day 9 post-infection. The results of this work indicate that the extract of Aloe secundiflora may be used in the control of fowl typhoid in chickens. Studies to determine the active ingredients of the plant extract are in progressen_US
dc.identifier.citationWaihenya, R.K., Mtambo, M.M.A., Nkwengulila, G. and Minga, U.M., 2002. Efficacy of crude extract of Aloe secundiflora against Salmonella gallinarum in experimentally infected free-range chickens in Tanzania. Journal of ethnopharmacology, 79(3), pp.317-323.en_US
dc.identifier.doi10.1016/S0378-8741(01)00397-X
dc.identifier.urihttp://hdl.handle.net/123456789/1478
dc.language.isoenen_US
dc.publisherElsevier Ireland Ltden_US
dc.subjectAloe secundifloraen_US
dc.subjectEfficacyen_US
dc.subjectSalmonella gallinarumen_US
dc.subjectFree-range local chickensen_US
dc.titleEfficacy of crude extract of Aloe secundiflora against Salmonella gallinarum in experimentally infected free-range chickens in Tanzaniaen_US
dc.typeJournal Articleen_US
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