Methyl­ ­D­glucopyranoside from Tulbghia violacea α Extract   Induces   Apoptosis   in   Vitro   in   Cancer   Cells

Methyl Dglucopyranoside from Tulbghia violacea α Extract Induces Apoptosis in Vitro in Cancer Cells

dc.contributor.author	Lyantagaye, Sylvester L.
dc.date.accessioned	2016-05-05T14:11:35Z
dc.date.available	2016-05-05T14:11:35Z
dc.date.issued	2013
dc.description.abstract	Pro-apoptotic activity of Tulbghia violacea extracts was evaluated in order to understand the mechanisms of action that might be related to its traditional use as anticancer medicine. Apoptosis-guided purification was used to isolate active compound whose chemical structure was solved by using spectroscopic, microanalysis and X-ray crystallography techniques. T. violacea extract kills Chinese hamster ovary cells, MCF7, and HeLa cells through the induction of apoptosis Methyl--D-glucopyranoside was identified as one of the main pro-apoptotic compounds present in T. violacea extract. This is the first time ever demonstration that T. violacea contains methyl -D-glucopyranoside, which selectively kills cancer cells through apoptosis mechanisms.	en_US
dc.identifier.citation	Lyantagaye, S.L., 2013. Methyl-α-D-glucopyranoside from Tulbaghia violacea extract induces apoptosis in vitro in cancer cells. Bangladesh Journal of Pharmacology, 8(2), pp.93-101.	en_US
dc.identifier.uri	http://hdl.handle.net/20.500.11810/1843
dc.language.iso	en	en_US
dc.subject	Apoptosis	en_US
dc.subject	Anti-cancer	en_US
dc.subject	Methyl-α-D-glucopyranoside	en_US
dc.subject	Tulbaghia violacea	en_US
dc.title	Methyl Dglucopyranoside from Tulbghia violacea α Extract Induces Apoptosis in Vitro in Cancer Cells	en_US
dc.type	Journal Article, Peer Reviewed	en_US