New Advances in CMV and Immunosenescence

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dc.contributor.authorSansoni, Paolo
dc.contributor.authorVescovini, Rosanna
dc.contributor.authorFagnoni, Francesco
dc.contributor.authorAkbar, Arne
dc.contributor.authorArens, Ramon
dc.contributor.authorChiu, Yen L.
dc.contributor.authorŠain, Luka Č.
dc.contributor.authorMerville, Julie D.
dc.contributor.authorDerhovanessian, Evelyna
dc.contributor.authorMartinez, Sara F.
dc.contributor.authorFranceschi, Claudio
dc.contributor.authorFrasca, Daniela
dc.contributor.authorFulöp, Tamas
dc.contributor.authorFurman, David
dc.contributor.authorKlotsas, Effrossyni G.
dc.contributor.authorGoodrum, Felicia
dc.contributor.authorLoebenstein, Beatrix G.
dc.contributor.authorHurme, Mikko
dc.contributor.authorKern, Florian
dc.contributor.authorLiller, Daniele
dc.contributor.authorBotet, Miguel L.
dc.contributor.authorMaier, Andrea B.
dc.contributor.authorMarandu, Thomas F.
dc.contributor.authorMarchant, Arnaud
dc.contributor.authorMatheï, Catharina
dc.contributor.authorMoss, Paul
dc.contributor.authorMuntasell, Aura
dc.contributor.authorRemmerswaal, Ester B.M.
dc.contributor.authorRiddell, Natalie E.
dc.contributor.authorRothe, Kathrin
dc.contributor.authorSauce, Delphine
dc.contributor.authorShin, Eui C.
dc.contributor.authorSimanek, Amanda M.
dc.contributor.authorSmithey, Megan J.
dc.contributor.authorNauclér, Cecilia S.
dc.contributor.authorSolana, Rafael
dc.contributor.authorThomas, Paul G
dc.contributor.authorLier, Rene V.
dc.contributor.authorPawelec, Graham
dc.contributor.authorZugich, Janko N.
dc.date.accessioned2016-07-08T07:09:54Z
dc.date.available2016-07-08T07:09:54Z
dc.date.issued2014-04
dc.description.abstractImmunosenescence, defined as the age-associated dysregulation and dysfunction of the immune system, is characterized by impaired protective immunity and decreased efficacy of vaccines. An increasing number of immunological, clinical and epidemiological studies suggest that persistent Cytomegalovirus (CMV) infection is associated with accelerated aging of the immune system and with several age-related diseases. However, current evidence on whether and how human CMV (HCMV) infection is implicated in immunosenescence and in age-related diseases remains incomplete and many aspects of CMV involvement in immune aging remain controversial. The attendees of the 4th International Workshop on "CMV & Immunosenescence", held in Parma, Italy, 25-27th March, 2013, presented and discussed data related to these open questions, which are reported in this commentary.en_US
dc.identifier.citationSansoni, P., Vescovini, R., Fagnoni, F.F., Akbar, A., Arens, R., Chiu, Y.L., Čičin-Šain, L., Dechanet-Merville, J., Derhovanessian, E., Ferrando-Martinez, S. and Franceschi, C., 2014. New advances in CMV and immunosenescence. Experimental gerontology, 55, pp.54-62.en_US
dc.identifier.doi10.1016/j.exger.2014.03.020 · Source: PubMed
dc.identifier.urihttp://hdl.handle.net/20.500.11810/2836
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.subjectImmunosenescenceen_US
dc.subjectCytomegalovirus infectionen_US
dc.subjectImmune homeostasisen_US
dc.subjectPathologies of agingen_US
dc.titleNew Advances in CMV and Immunosenescenceen_US
dc.typeJournal Article, Peer Revieweden_US
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