Computational Modelling of Cholera Bacteriophage with Treatment

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dc.contributor.authorMgonja, Daniel S.
dc.contributor.authorMassawe, Estomih S.
dc.contributor.authorMakinde, Oluwole D.
dc.date.accessioned2016-06-26T17:13:46Z
dc.date.available2016-06-26T17:13:46Z
dc.date.issued2015
dc.description.abstractThis paper examines the computational modelling of cholera bacteriophage with treatment. A nonlinear mathematical model for cholera bacteriophage and treatment is formulated and analysed. The effective reproduction number of the nonlinear model system is calculated by next generation operator method. By using the next generation matrix approach, the disease-free equilibrium is found to be locally stable at threshold parameter less than unity and unstable at threshold parameter greater than unity. Globally, the disease free equilibrium point is not stable due to existence of forward bifurcation at threshold parameter equal to unity. Stability analysis and numerical simulations suggest that the combination of bacteriophage and treatment may contribute to lessening the severity of cholera epidemics by reducing the number of Vibrio cholerae in the environment. Hence with the presence of bacteriophage virus and treatment, cholera is self-limiting in nature.en_US
dc.identifier.citationMgonja, D.S., Massawe, E.S. and Makinde, O.D., 2015. Computational Modelling of Cholera Bacteriophage with Treatment. Open Journal of Epidemiology, 5(03), p.172.en_US
dc.identifier.doi10.4236/ojepi.2015.53022
dc.identifier.urihttp://hdl.handle.net/20.500.11810/2718
dc.language.isoenen_US
dc.publisherScientific Researchen_US
dc.subjectCholeraen_US
dc.subjectBacteriophageen_US
dc.subjectTreatmenten_US
dc.subjectVibrio choleraeen_US
dc.subjectEquilibriumen_US
dc.subjectStabilityen_US
dc.subjectEffective Reproduction Numberen_US
dc.titleComputational Modelling of Cholera Bacteriophage with Treatmenten_US
dc.typeJournal Article, Peer Revieweden_US
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