Dietary L-carnitine supplementation recovers the increased pH and hardness in fillets caused by high-fat diet in Nile tilapia (Oreochromis niloticus)

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dc.contributor.authorZhi-Yong Zhang
dc.contributor.authorSamwel Mchele Limbu
dc.contributor.authorSi-Han Zhao
dc.contributor.authorLi-Qiao Chen
dc.contributor.authorYuan Luo
dc.contributor.authorMei-Ling Zhang
dc.contributor.authorFang Qiao
dc.contributor.authorZhen-Yu Du
dc.date.accessioned2022-08-05T16:10:47Z
dc.date.available2022-08-05T16:10:47Z
dc.date.issued2022-07-15
dc.description.abstractThe wide use of high-fat diet (HFD) causes negative effects on flesh quality in farmed fish. l-carnitine, a lipid-lowering additive, enhances mitochondrial fatty acid β-oxidation. However its roles in alleviating the effects of HFD on flesh quality in fish are unknown. We fed Nile tilapia with medium-fat diet (MFD, 6% dietary lipid), high-fat diet (HFD, 12% dietary lipid) and HFCD supplemented with l-carnitine (HFCD + 400 mg/kg l-carnitine) for 10 weeks. The HFD-fed fish had higher fat deposition, pH value, myofiber density and flesh hardness than those fed on MFD. However, feeding the fish with the HFCD improved lipid catabolism, which increased significantly lactic acid content and myofiber diameter in muscle, thus reduced pH and hardness values. HFCD also reduced endoplasmic reticulum stress and myofiber apoptosis caused by HFD in the fish. Our study suggests that dietary l-carnitine supplementation alleviates the negative effects of HFD on flesh quality of farmed fish.en_US
dc.description.sponsorshipNational Key R&D Program of China (2018YFD0900400)en_US
dc.identifier.citationZhi-Yong Zhang, Samwel M. Limbu, Si-Han Zhao, Li-Qiao Chen, Yuan Luo, Mei-Ling Zhang, Fang Qiao, and Zhen-Yu Du (2022). Dietary L-carnitine supplementation recovers the increased pH and hardness in fillets caused by high-fat diet in Nile tilapia (Oreochromis niloticus), Food Chemistry, 382: 132367. https://doi.org/10.1016/j.foodchem.2022.132367.en_US
dc.identifier.doihttps://doi.org/10.1016/j.foodchem.2022.132367
dc.identifier.urihttp://hdl.handle.net/20.500.11810/5876
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.subjectAquacultureen_US
dc.subjectDietary lipiden_US
dc.subjectLipid catabolismen_US
dc.subjectFlesh qualityen_US
dc.subjectMyofibersen_US
dc.subjectpH valueen_US
dc.titleDietary L-carnitine supplementation recovers the increased pH and hardness in fillets caused by high-fat diet in Nile tilapia (Oreochromis niloticus)en_US
dc.typeJournal Article, Peer Revieweden_US
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