Antiviral Activity of the Crude Extracts and Phytochemical Fractions of Aloe Secundiflora against Newcastle Disease Virus

Simple item page
dc.contributor.authorWaihenya, R. K.
dc.contributor.authorKeriko, J. M.
dc.contributor.authorMtambo, M. M. A.
dc.contributor.authorNkwengulila, Gamba
dc.contributor.authorKayser, O.
dc.contributor.authorHafez, H. M.
dc.date.accessioned2016-04-12T13:15:32Z
dc.date.available2016-04-12T13:15:32Z
dc.date.issued2005
dc.descriptionFull text can be accessed at http://www.ajol.info/index.php/jtmb/article/view/35434en_US
dc.description.abstractCrude extract of Aloe secundiflora (Aloeaceae), and three phytochemical (HPLC) fractions containing the major phenolic compounds were investigated for their effects on Newcastle Disease Virus (NDV) in embryonated specific pathogen free (SPF) chicken eggs. The three fractions used contained the major peaks within which the main compounds had been identified as aloenin, aloin and an aloinoside derivatives. The crude Aloe extract at 400 mg/ml exhibited antiviral effects at 100%, While 200 mg/ml resulted to 30% reduction in viral multiplication. Fraction containing aloenin (4 mg/ml = 4000 ppm) also showed 100% reduction effects of viral multiplication on NDV in nineday old embryonated chicken eggs (ECE). Fraction containing aloin (4 mg/ml = 4000 ppm) exhibited 50% reduction of viral multiplication while the fraction containing aloinside showed 70% reduction effects. The results of the study provided a justification on the ethnoveterinary use of the exudate in the prophylaxis / control of Newcastle Disease Virus.en_US
dc.identifier.citationWaihenya, R.K., Keriko, J.M., Mtambo, M.M.A., Nkwengulila, G., Kayser, O. and Hafez, H.M., 2005. Antiviral activity of the crude extracts and phytochemical fractions of Aloe secundiflora against Newcastle Disease Virus. Journal of Tropical Microbiology and Biotechnology, 1(1), pp.10-13.en_US
dc.identifier.doi10.4314/jtmb.v1i1.35434
dc.identifier.urihttp://hdl.handle.net/123456789/1512
dc.language.isoenen_US
dc.subjectAloe secundifloraen_US
dc.subjectAloaceae Newcastle Disease Virusen_US
dc.subjectEthnoveterinaryen_US
dc.subjectAnthraquinonesen_US
dc.subjectAloeninen_US
dc.subjectAloinen_US
dc.titleAntiviral Activity of the Crude Extracts and Phytochemical Fractions of Aloe Secundiflora against Newcastle Disease Virusen_US
dc.typeJournal Article, Peer Revieweden_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Antiviral Activity of the Crude Extracts and Phytochemical Fractions of Aloe Secundiflora against Newcastle Disease Virus.pdf
Size:
84.53 KB
Format:
Adobe Portable Document Format
Description:
Abstract
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Department of Zoology and Wildlife Conservation