Predictors of Antibiotics Co-Prescription with Antimalarials for Patients Presenting With Fever in Rural Tanzania

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dc.contributor.authorNjozi, Mustafa
dc.contributor.authorAmuri, Mbaraka
dc.contributor.authorSelemani, Majige
dc.contributor.authorMasanja, Irene M.
dc.contributor.authorKigahe, Brown
dc.contributor.authorKhatib, Rashid A.
dc.contributor.authorDan, Kajungu
dc.contributor.authorAbdulla, Salim
dc.contributor.authorDodoo, Alexander
dc.date.accessioned2016-07-08T12:02:28Z
dc.date.available2016-07-08T12:02:28Z
dc.date.issued2013-11
dc.description.abstractSuccessful implementation of malaria treatment policy depends on the prescription practices for patients with malaria. This paper describes prescription patterns and assesses factors associated with co-prescription of antibiotics and artemether-lumefantrine (AL) for patients presenting with fever in rural Tanzania. From June 2009 to September 2011, a cohort event monitoring program was conducted among all patients treated at 8 selected health facilities in Ifakara and Rufiji Health and Demographic Surveillance System (HDSS).It included all patients presenting with fever and prescribed with AL. Logistic regression was used to model the predictors on the outcome variable which is co-prescription of AL and antibiotics on a single clinical visit. A cohort of 11,648 was recruited and followed up with 92% presenting with fever. Presumptive treatment was used in 56% of patients treated with AL. On average 2.4 (1 -- 7) drugs was prescribed per encounter, indicating co-prescription of AL with other drugs. Children under five had higher odds of AL and antibiotics co-prescription (OR = 0.63, 95% CI: 0.46 -- 0.85) than those aged more than five years. Patients testing negative had higher odds (OR = 2.22, 95%CI: 1.65 -- 2.97) of AL and antibiotics co-prescription. Patients receiving treatment from dispensaries had higher odds (OR = 1.45, 95% CI: 0.84 -- 2.30) of AL and antibiotics co-prescription than those from served in health centres even though the deference was not statistically significant. Regardless the fact that Malaria is declining but due to lack of laboratories and mRDT in most health facilities in the rural areas, clinicians are still treating malaria presumptively. This leads them to prescribe more drugs to treat allen_US
dc.identifier.citationNjozi, M., Amuri, M., Selemani, M., Masanja, I., Kigahe, B., Khatib, R., Kajungu, D., Abdula, S. and Dodoo, A.N., 2013. Predictors of antibiotics co-prescription with antimalarials for patients presenting with fever in rural Tanzania. BMC Public Health, 13(1), p.1.en_US
dc.identifier.doi10.1186/1471-2458-13-1097 · Source: PubMed
dc.identifier.urihttp://hdl.handle.net/20.500.11810/2882
dc.language.isoenen_US
dc.subjectCohort event monitoringen_US
dc.subjectAntibioticsen_US
dc.subjectCo-prescriptionen_US
dc.subjectArtemether-lumefantrineen_US
dc.subjectTanzaniaen_US
dc.titlePredictors of Antibiotics Co-Prescription with Antimalarials for Patients Presenting With Fever in Rural Tanzaniaen_US
dc.typeJournal Article, Peer Revieweden_US
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