Facile Synthesis of Acacetin-7-O-β-d-Galactopyranoside
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Date
2011-12
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Abstract
Acacetin-7-O-β-d-galactopyranoside (1), a natural flavonoid isolated from flower heads of Chrysanthemum morifolium, has been reported to inhibit the replication of HIV in H9 cells. We achieved the total synthesis of compound 1 by employing a one-pot synthesis of the aglycon. The key reactions in this approach include the modified Baker–Venkataraman reaction and regio- and stereoselective O-glycosylations.
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http://www.sciencedirect.com/science/article/pii/S0008621511005714
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Zacharia, J.T. and Hayashi, M., 2012. Facile synthesis of acacetin-7-O-β-D-galactopyranoside. Carbohydrate research, 348, pp.91-94.