Crystallization and preliminary X-ray analysis of the human c-H-ras-oncogene product p21 complexed with GTP analogues

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Crystallization and preliminary X-ray analysis of the human c-H-ras-oncogene product p21 complexed with GTP analogues.pdf (67.27 KB)
Date
1989-03
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Elsevier
Abstract
The catalytic domain (amino acid residues 1 to 166) of the human ras-oncogene product p21 complexed with the GTP analogues beta,gamma-imido-GTP (GMPPNP), beta,gamma-methylene-GTP (GMPPCP), and guanosine-5'-(gamma-thiotriphosphate) (GTP gamma S) have been been crystallized. Crystals of the GMPPNP and GMPPCP complexes are well suited for high resolution X-ray crystallography. They belong to space group P3(1)21 (or its enantiomorph P3(2)21) with unit cell axes a=b=40.3 A and c = 162.2 A.
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Full text can be accessed at http://www.sciencedirect.com/science/article/pii/0022283689905408
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Scherer, A., John, J., Linke, R., Goody, R.S., Wittinghofer, A., Pai, E.F. and Holmes, K.C., 1989. Crystallization and preliminary X-ray analysis of the human cH-ras-oncogene product p21 complexed with GTP analogues. Journal of molecular biology, 206(1), pp.257-259.
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http://hdl.handle.net/20.500.11810/3223
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Department of Zoology and Wildlife Conservation