Extent of Morbidity Associated with Schistosomiasis Infection in Malawi: A Review Paper

dc.contributor.authorMtethiwa, Austin H. N.
dc.contributor.authorNkwengulila, Gamba
dc.contributor.authorBakuza, Jared S.
dc.contributor.authorSikawa, Daniel
dc.contributor.authorKazembe, Abigail
dc.date.accessioned2016-04-14T05:56:06Z
dc.date.available2016-04-14T05:56:06Z
dc.date.issued2015
dc.description.abstractData on the extent of the burden due to schistosomiasis is sparse in most Sub-Saharan African countries. However, this data is crucial for triggering medical attention. A review of extent of morbidity and determinants associated with schistosomiasis in Malawi was therefore conducted to quantify the infection in order to concretise the need for medical intervention. A systematic and traditional search strategy was used to find literature for the review, whilst exclusion and inclusion criteria were used to identify appropriate articles. Logistic regression curves of epidemiological model Y = (a + bxc )/(1 + bxc ) and the recommendation that schistosomiasis prevalence can be used to estimate morbidity were employed to quantify morbidity at various infection stages. Morbidity was quantified as a direct proportion of the population and the respective national schistosomiasis prevalence. Findings showed that both S. mansoni and S. haematobium are present in Malawi with the latter highly prevalent (50%). Furthermore, out of the estimated population of 16,829 million, approximately 8.4 million have schistosomiasis, with about 4.4 million of these aged 18 years and below. The most frequent manifestation is Katayama syndrome, while ascites is the lowest, impacting about 3.0 million and 960 individuals, respectively. Localised studies on association of schistosomiasis infection to risk factors such as occupation, age and gender found odds ratio (OR) ranging from 1.29 to 5.37. Morbidity due to schistosomiasis is high in Malawi. It is therefore recommended that a more detailed study on the determinants of high schistosomiasis and re-evaluation of the current control measures be conducted if the current morbidity statistics are to be remarkably reduced.en_US
dc.identifier.citationMtethiwa, A.H., Nkwengulila, G., Bakuza, J., Sikawa, D. and Kazembe, A., 2015. Extent of morbidity associated with schistosomiasis infection in Malawi: a review paper. Infectious diseases of poverty, 4(1), p.25.en_US
dc.identifier.doi10.1186/s40249-015-0053-1
dc.identifier.urihttp://hdl.handle.net/123456789/1526
dc.language.isoenen_US
dc.publisherBioMed Centralen_US
dc.subjectSchistosomiasisen_US
dc.subjectMorbidityen_US
dc.subjectRisk factorsen_US
dc.subjectQuantificationen_US
dc.subjectBurdenen_US
dc.subjectExtenten_US
dc.titleExtent of Morbidity Associated with Schistosomiasis Infection in Malawi: A Review Paperen_US
dc.typeJournal Article, Peer Revieweden_US
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