Browsing by Author "Wepierre, J."
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Item Comparative Study of Absorption and Distribution of Dexamethasone-3H after Percutaneous or Oral Administration in Mice and Rats](1975-12) James, Makungu; Marty, J. P.; Wepierre, J.Percutaneous absorption of dexamethasone in alcoholic solution in mice and rats was low. Permeability constant measured on mice was included between 1.05 and 1.39.10(-5) cm/h. Under the site of application, a retention appeared in subcutaneous tissue and skeletal muscles which explained local pharmacological action. In other tissues (plasma, liver, kidney, adrenals and muscles), level of corticoid remained very low. On the contrary after oral administration, dexamethasone was present everywhere, concentration was the highest in liver and kidney.Item Effect of Dimethylsulfoxide, Dimethylformamide and Diethylformamide on the Percutaneous Absorption of Eserine in Rats(1966-11) Wepierre, J.; Nouvel, G.; Cabanne, F.; James, MakunguItem Localized Diffusion of Substances Absorbed Through the Skin(1974-05) James, Makungu; Marty, J. P.; Wepierre, J.Item Percutaneous Absorption in Vivo of $Sup 125$I-Thyroxine and $Sup 125$I- Triiodothyronine in the Rat(1974-01) James, Makungu; Wepierre, J.