Lyantagaye, Sylvester L.2016-05-052016-05-052013Lyantagaye, S.L., 2013. Methyl-α-D-glucopyranoside from Tulbaghia violacea extract induces apoptosis in vitro in cancer cells. Bangladesh Journal of Pharmacology, 8(2), pp.93-101.http://hdl.handle.net/20.500.11810/1843Pro-apoptotic activity of Tulbghia violacea extracts was evaluated in order to understand the mechanisms of action that might be related to its traditional use as anticancer medicine. Apoptosis-guided purification was used to isolate active compound whose chemical structure was solved by using spectroscopic, microanalysis and X-ray crystallography techniques. T. violacea extract kills Chinese hamster ovary cells, MCF7, and HeLa cells through the induction of apoptosis Methyl--D-glucopyranoside was identified as one of the main pro-apoptotic compounds present in T. violacea extract. This is the first time ever demonstration that T. violacea contains methyl -D-glucopyranoside, which selectively kills cancer cells through apoptosis mechanisms.enApoptosisAnti-cancerMethyl-α-D-glucopyranosideTulbaghia violaceaJournal Article, Peer Reviewed