Haider, M. SalmanShao, Godlisten N.Ahmad, AhmadImran, S. MuhammadAbbas, NadirAbbas, GhulamHussein, ManwarKim, Hee Taik2019-06-112019-06-112019-03-11http://hdl.handle.net/20.500.11810/5242This study demonstrates a novel, facile and one-pot approach to synthesize silica nanoparticles with silver at core and crust (SiNP-AgCC). A modified Stöber method was used to make SiNP-AgCC. A significant reduction in the size of SiO2 nanoparticles was seen, with 2–5 nm AgNPs being uniformly distributed on the surface and 10–20 nm AgNPs in the center. A typical mesoporous SiO2 particle (SiNP) produced using the Stöber method was transformed to nanoporous SiO2 by this modified Stöber method. Nanoporous SiO2 particles with silver in the center are advantageous for slow and consistent Ag+ release, which was confirmed by Ag+ ion release test. Antibacterial activities of the samples were tested to evaluate the disinfection performance of the samples on gram-negative bacteria (Escherichia coli) using disk diffusion and the LB-agar method. SiNP-AgCC showed prolonged silver release for more than 20 days and improved antibacterial properties even after five days of incubation.enSiO2-AgNPs nanocompositeSiO2-AgNPs @ Core and CrustModified Stöber methodSilver releaseAntibacterial propertiesFacile, Single-pot preparation of nanoporous SiO2 particles (carrier) with AgNPs at core and crust for controlled disinfectant releaseFacile, Single-pot preparation of nanoporous SiO2 particles (carrier) with AgNPs at core and crust for controlled disinfectant releaseJournal Article, Peer Reviewed